On July 19, 2022, the Chinese Ministry of Ecology and Environment (MEE) published a notice, announcing that 22 substances were included in the Inventory of Existing Chemical Substances (IECSC). The addition was under consultation from April 28 to May 13, 2022.
These 22 chemical substances were manufactured in or imported into China before October 15, 2003, which fulfilled the supplementation criteria but missed the previous supplementation window. They are now regulated as existing chemical substances in China, and thus free from new chemical registration or notification requirements under the Measures for the Ecology and Environmental Management Registration of New Chemical Substances (MEE Order No.12).
22 Subasatances Added into IECSC
| No. | Name | Chemical Formula | CAS No. |
| 1. | 1,8-Diaminonaphthalene | C10H10N2 | 479-27-6 |
| 2. | 4-Chloro-3,5-dinitrobenzotrifluoride | C7H2ClF3N2O4 | 393-75-9 |
| 3. | m-Nitrotrifluorotoluene | C7H4F3NO2 | 98-46-4 |
| 4. | 3-Cyclopentylpropanoyl chloride | C8H13ClO | 104-97-2 |
| 5. | 3-Cyclohexylpropionic acid | C9H16O2 | 701-97-3 |
| 6. | Ammonium O,O-diisopropylthiophosphate | C6H18NO3PS | 29918-57-8 |
| 7. | 1-Bromo-4-(methylamino)anthraquinone | C15H10BrNO2 | 128-93-8 |
| 8. | 4,7-Dichloroquinoline | C9H5Cl2N | 86-98-6 |
| 9. | 3,5,6-Trichloro-2- hydroxybenzoic acid | C7H3Cl3O3 | 40932-60-3 |
| 10. | 2,4,5-Trifluoro-3-methoxybenzoyl chloride | C8H4ClF3O2 | 112811-66-2 |
| 11. | Sodium N-chlorobenzenesulfonamide | C6H5ClNNaO2S | 127-52-6 |
| 12. | Benzene, ethyl(1-phenylethyl)- | C16H18 | 35254-73-0 |
| 13. | (6R,7R)-7-[2-(furan-2-yl)-2-(methoxyimino)acetamido]-3-carbamoyloxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | C16H16N4O8S | 55268-75-2 |
| 14. | (6R,7R)-7-[2-furanyl(methoxyimino)acetylamino]-3-hydroxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | C15H15N3O7S | 56271-94-4 |
| 15. | 1,3-Bisbenzyl-2-oxoimidazolidine-4,5- dicarboxylic acid | C19H18N2O5 | 59564-78-2 |
| 16. | 1-Isopropyl-3-tert-butylthiourea | C8H18N2S | 52599-24-3 |
| 17. | (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy- 1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride | C22H22O7N6 S2· 2HCl | 73547-70-3 |
| 18. | N’-Methyl-N,N-diphenyl urea | C14H14N2O | 13114-72-2 |
| 19. | N,N’-Diethyl-N,N’-diphenylurea | C17H20N2O | 85-98-3 |
| 20. | N-Chloromethyl-N-phenylcarbamoyl chloride | C8H7Cl2NO | 52123-54-3 |
| 21. | Chromate(5-),bis[5-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl- 1H-pyrazol-4-yl)azo]-4-hydroxy-3-benzenedisulfonato(4-)]-, tetrasodium hydrogen | C32H20CrN8O16S4 ·H ·4Na | 68541-69-5 |
| 22. | Trisodium [ 1,2′-(2-(8-amino-3,5-disulfonatonaphthalene)azo)-(4′-nitrobenzene)diolato-O,O,N][(Z)-2,2-((phenylcarbamoylprop-1′-enyl)azo)-5-sulfamoylbenzene)diolato-O,O,N]chromate(III) | C32H22CrN8O15S3 ·3Na | 371973-51-2 |
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