China New Cosmetic Ingredient Success Story: Peptites' Cyclic Peptide

The ingredient, Cyclo (Glycyl s-Brine Shrimp Octapeptide-1 Glycine), is notified under the Chinese name 环（甘氨酰 s-丰年虾八肽-1 甘氨酸）. It is a cyclic peptide developed in-house by Peptites for cosmetic applications.

REACH24H's Support in the Notification Process

As the project's technical service provider, REACH24H worked closely with Peptites throughout the notification process. Ingredient name standardization was one of the key areas in which the team provided professional support, helping the company address an important aspect of its NCI submission.

The project builds on a long-standing collaboration between REACH24H and Peptites. Through close technical communication and coordinated project activities, the two teams brought this latest ingredient notification to completion.

About Zhejiang Peptites Biotech Co., Ltd.

Founded in 2015, Peptites specializes in the research, development, production and supply of peptide products and related services. Recognized as a national-level specialized and innovative "Little Giant" enterprise, the company has established capabilities in peptide synthesis, purification and large-scale production, supplying both cosmetic peptide ingredients and pharmaceutical peptide products.

For cosmetic ingredient developers, Peptites offers integrated support spanning early-stage development, research and experimentation, peptide powder production, solution formulation, stability testing and efficacy evaluation. Its research infrastructure includes a postdoctoral research workstation and a Shaoxing academician and expert workstation, supporting the development of peptide technologies and applications.

REACH24H's Broader Experience in New Cosmetic Ingredients

Beyond this cyclic peptide project, REACH24H has helped companies complete more than 60 new cosmetic ingredient registration and notification projects. This experience covers plant-derived ingredients, fermentation- and biotechnology-derived ingredients, chemically synthesized ingredients, peptides, polymers and ingredients from edible sources. Across this broader project portfolio, intended uses include skin whitening and dark-spot reduction, anti-wrinkle care, hair care, moisturization and antioxidant functions.

The team has practical experience in assessing safe consumption history and overseas safe-use history, using existing toxicological data, and applying non-animal testing methods, where appropriate under applicable Chinese requirements. REACH24H also advises on toxicological and stability study design, helping companies plan the research needed to support their ingredient submissions.

How REACH24H Can Help

REACH24H's cosmetic compliance team comprises 42 full-time technical experts, with expertise spanning regulatory assessment, toxicology, safety assessment, efficacy evaluation and responses to technical review questions. The team includes toxicologists holding certification or registration credentials from China, Europe, the United Kingdom and the United States, including DCST, ERT, UKRT and DABT.

For companies developing new cosmetic ingredients, REACH24H provides regulatory and technical support across:

• Registration and notification projects;

• Study planning; and

• Cosmetic safety assessment.

Beyond cosmetics, its services also cover pharmaceutical, new food ingredient and chemical compliance, supporting businesses with regulatory needs across multiple product categories.

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